Production and characterization of monoclonal antibodies to the c-erbB-2 proto-oncogene protein using a synthetic peptide immunogen.
نویسندگان
چکیده
NADIA L. TUZI,* DEON J. VENTER,? JACKIE A. REIDLINGER,$ CHRISTOPHER J. DEAN$ and WILLIAM J. GULLICK* *Imperial Cancer Research Fund Oncology Group, M. R. C. Cyclotron Building, Hummersmith Hospital, Du Cane Road, London WI2 OHS, U .K . , tLudwig Institute for Cancer Research, 91 Riding House Street, London WIP 8BT, U.K. and $Institute of Cancer Research, Section of Medicine, CIifOn Avenue, Belmont, Sutton, surrey SM2 5px, U.K. The growth of cells is, in part, regulated by the concentration of polypeptide growth factors in the extracellular compartAbbreviations used: EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; TGF, transforming growth factor; IGF, insulin-like growth factor; RIA, radioimmunoassay; ELISA, enzyme-linked immunosorbent assay.
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 16 5 شماره
صفحات -
تاریخ انتشار 1988